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Verified Service Provider in South Sudan

Genomics Core Facilities in South Sudan Engineering Excellence & Technical Support

Genomics Core Facilities solutions for Research & Discovery (R&D). High-standard technical execution following OEM protocols and local regulatory frameworks.

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Advanced DNA Sequencing Capabilities

Empowering South Sudan's research with cutting-edge Next-Generation Sequencing (NGS) platforms, enabling rapid and comprehensive analysis of genetic material for disease surveillance, agricultural improvement, and biodiversity studies.

Pathogen Genomics for Public Health

Providing critical genomic data to track infectious disease outbreaks, identify antimicrobial resistance patterns, and inform public health interventions, strengthening South Sudan's capacity to combat prevalent and emerging pathogens.

Agricultural Genomics for Food Security

Supporting the development of climate-resilient and high-yield crops through genomic analysis, contributing to improved agricultural practices and enhanced food security for communities across South Sudan.

What Is Genomics Core Facilities In South Sudan?

Genomics Core Facilities in South Sudan, while nascent, represent a crucial infrastructure for advancing biological research, diagnostics, and public health initiatives. These facilities provide centralized access to specialized equipment, technical expertise, and standardized protocols for performing a wide range of genomic analyses. Their establishment aims to democratize access to advanced genomic technologies, which are often prohibitively expensive for individual research groups or institutions, thereby fostering a more robust and competitive scientific landscape within the country.

Who Needs Genomics Core FacilitiesTypical Use Cases
Academic and Research Institutions: Universities, research centers, and government agencies seeking to conduct fundamental biological research, identify genetic underpinnings of diseases, or explore biodiversity.Public Health Laboratories: National and regional health bodies requiring genomic surveillance for infectious diseases (e.g., pathogen identification, tracking outbreaks, antimicrobial resistance profiling), as well as for genetic screening and diagnostics.Clinical Diagnostic Laboratories: Hospitals and specialized clinics performing genetic testing for inherited disorders, cancer predisposition, pharmacogenomics, and prenatal diagnostics.Agricultural and Veterinary Sectors: Institutions involved in crop improvement, livestock breeding, disease diagnosis in animals, and food security research.Environmental and Conservation Agencies: Organizations studying wildlife genomics, population genetics, biodiversity assessment, and ecological monitoring.Biotechnology Companies (emerging): Start-ups and established companies in the biopharmaceutical, agricultural, or industrial biotechnology sectors requiring genomic data for product development or validation.
Infectious Disease Surveillance and Outbreak Response: Rapid identification of novel pathogens, tracking the spread of known diseases (e.g., malaria, tuberculosis, HIV, emerging viral threats), and monitoring the evolution of drug resistance and virulence factors.Rare and Inherited Disease Diagnosis: Identifying genetic mutations responsible for rare diseases to facilitate diagnosis, genetic counseling, and potential therapeutic development.Cancer Genomics: Characterizing tumor heterogeneity, identifying driver mutations for targeted therapies, and monitoring treatment response.Pharmacogenomics: Predicting individual drug responses based on genetic makeup, optimizing drug selection and dosage, and minimizing adverse drug reactions.Agricultural Genomics: Identifying genes associated with desirable traits in crops and livestock (e.g., yield, disease resistance, drought tolerance) for breeding programs.Biodiversity and Conservation Genomics: Understanding genetic diversity within populations, identifying genetically distinct units for conservation efforts, and monitoring the impact of environmental changes.Forensic Genomics: DNA profiling for identification purposes in criminal investigations or disaster victim identification.Population Genetics Studies: Investigating human migration patterns, evolutionary history, and genetic adaptations within specific populations in South Sudan.

What a Genomics Core Facility Service Involves

  • High-throughput DNA/RNA sequencing (e.g., Illumina, Oxford Nanopore platforms) for whole-genome, exome, transcriptome, and epigenome profiling.
  • Genotyping services, including SNP arrays and microsatellite analysis.
  • Next-generation sequencing (NGS) library preparation and quality control.
  • Bioinformatics support for data processing, alignment, variant calling, and downstream analysis (e.g., differential gene expression, pathway analysis).
  • Sample quality assessment (e.g., DNA/RNA integrity and quantity determination using spectrophotometry and fluorometry).
  • Custom assay design and development.
  • Training and consultation on experimental design, protocol optimization, and data interpretation.
  • Data management and storage solutions.
  • Potential integration with other omics platforms (proteomics, metabolomics) as capabilities expand.

Who Needs Genomics Core Facilities In South Sudan?

South Sudan, a nation grappling with significant health challenges and a developing research infrastructure, can greatly benefit from dedicated genomics core facilities. These facilities are crucial for advancing our understanding of local diseases, improving diagnostics, developing targeted therapies, and building local scientific capacity. The potential impact spans multiple sectors, from public health and agriculture to education and biosecurity.

Customer TypeKey Departments/SectorsPrimary Genomics Applications
Public HealthMinistry of Health, National Public Health LaboratoryPathogen surveillance, outbreak tracing, antimicrobial resistance monitoring, vaccine development support, diagnostic assay development
Clinical ResearchUniversity Teaching Hospitals, Research Centers, Private ClinicsDiagnostic genomics (rare diseases, cancer), pharmacogenomics, personalized medicine, clinical trial support
AgricultureMinistry of Agriculture and Food Security, National Agricultural Research Organization (NARO), UniversitiesCrop and livestock breeding for resilience and productivity, disease diagnostics, pest management, food security initiatives
AcademiaUniversities (e.g., University of Juba, Upper Nile University), Research InstitutesBasic research, training of next-generation scientists, student projects, development of local research capacity
Government & PolicyRelevant Ministries (Health, Agriculture, Environment, Justice)Evidence-based policy formulation, national health security, biosecurity, environmental impact assessment, forensic investigations
Humanitarian & DevelopmentInternational NGOs, UN Agencies (e.g., WHO, UNICEF)Targeted health interventions, disease control programs, capacity building, emergency response genomics
Veterinary ServicesMinistry of Livestock and Fisheries, Veterinary HospitalsAnimal disease surveillance, diagnostics, livestock improvement, zoonotic disease tracking

Target Customers and Departments for Genomics Core Facilities in South Sudan

  • Public Health Sector: Essential for understanding and combating infectious diseases prevalent in South Sudan, such as malaria, tuberculosis, HIV/AIDS, and emerging pathogens. Genomics can identify disease strains, track outbreaks, and inform vaccine development and drug resistance monitoring.
  • Clinical Research Institutions & Hospitals: To offer advanced diagnostic capabilities, personalize treatment approaches for various conditions (e.g., cancer, genetic disorders), and support clinical trials with genetic profiling.
  • Agricultural Research & Development: To improve crop yields, enhance disease resistance in livestock and crops, and develop climate-resilient varieties, directly impacting food security and livelihoods.
  • Academic & Research Institutions (Universities): To provide students and researchers with cutting-edge tools for genetic research, fostering a new generation of scientists and driving fundamental discoveries relevant to South Sudan's specific environmental and health landscape.
  • Government Agencies (e.g., Ministry of Health, Ministry of Agriculture, Ministry of Environment): For evidence-based policymaking, public health surveillance, biosecurity (e.g., tracking zoonotic diseases), and environmental monitoring.
  • Non-Governmental Organizations (NGOs) & International Aid Organizations: Collaborating on disease eradication programs, health interventions, and capacity building initiatives, leveraging genomics for more effective and targeted aid.
  • Forensic Science Departments: For criminal investigations, identification of victims, and establishing familial relationships, enhancing the justice system.
  • Veterinary Services: To monitor and control animal diseases, improving livestock health and productivity, a cornerstone of many South Sudanese economies.

Genomics Core Facilities Process In South Sudan

The Genomics Core Facilities process in South Sudan, while still developing, follows a general workflow from initial inquiry to the execution of genomic services. This process is crucial for enabling research, diagnostics, and other applications that rely on genetic information. The workflow typically involves several key stages, designed to ensure clarity, efficiency, and quality of results.

StageDescriptionKey ActivitiesResponsible Party/Parties
Inquiry and ConsultationThe initial contact where a researcher or client expresses interest in genomics services. This stage is crucial for understanding project needs and feasibility.Contacting the facility, discussing research goals, project scope, budget, required services (e.g., DNA sequencing, RNA sequencing, genotyping), and timeline. Providing preliminary quotes or estimates.Researcher/Client, Genomics Core Facility Staff (e.g., Facility Manager, Scientific Staff)
Sample Submission and Quality ControlOnce a project is agreed upon, samples are submitted to the facility. Rigorous quality control is essential before proceeding to expensive downstream processes.Formal project initiation (e.g., service agreement, purchase order). Sample collection, transport, and logging. DNA/RNA extraction (if not provided by client). Assessment of sample quantity, purity, and integrity (e.g., using NanoDrop, Qubit, gel electrophoresis, bioanalyzer).Researcher/Client (sample collection, transport), Genomics Core Facility Staff (extraction, QC)
Library PreparationGenomic material (DNA/RNA) is prepared for sequencing by converting it into a 'library' of fragments with adapter sequences.Library construction based on the specific sequencing technology and application. This can involve fragmentation, end-repair, adapter ligation, and amplification. Further QC of prepared libraries (e.g., concentration, insert size distribution).Genomics Core Facility Staff
SequencingThe prepared libraries are loaded onto a sequencing instrument, where the genetic code is read.Loading libraries onto sequencing platforms (e.g., Illumina, Oxford Nanopore). Running the sequencing instrument according to established protocols. Monitoring sequencing run progress and quality metrics.Genomics Core Facility Staff
Data AnalysisRaw sequencing data is processed and analyzed to extract meaningful biological information.Base calling (converting raw signal data to nucleotide sequences). Quality assessment of raw reads. Read trimming and alignment to a reference genome. Variant calling, gene expression quantification, or other application-specific analyses. Statistical analysis.Genomics Core Facility Staff (bioinformaticians), Researcher/Client (for biological interpretation)
Data Delivery and InterpretationThe analyzed data is delivered to the client, along with any necessary documentation and support for interpretation.Generating reports (e.g., sequence files, variant lists, gene expression tables). Providing raw data files. Discussing results and assisting with biological interpretation. Archiving data.Genomics Core Facility Staff (bioinformaticians), Researcher/Client (biological interpretation)
Billing and ReportingThe final stage involves financial reconciliation and project closure.Issuing invoices based on services rendered. Processing payments. Providing final project reports and documentation.Genomics Core Facility Staff (administrative), Researcher/Client (payment)

Genomics Core Facility Workflow Stages:

  • Inquiry and Consultation
  • Sample Submission and Quality Control
  • Library Preparation
  • Sequencing
  • Data Analysis
  • Data Delivery and Interpretation
  • Billing and Reporting

Genomics Core Facilities Cost In South Sudan

Genomics core facilities in South Sudan are still in their nascent stages of development, with limited availability and a scarcity of specialized equipment and trained personnel. Consequently, pricing for genomic services can be highly variable and often reflect the costs associated with importing reagents, maintaining infrastructure in a challenging environment, and compensating skilled technicians. Factors influencing cost include the complexity of the assay, the volume of samples, the type of sequencing or analysis required, and the specific institution or provider offering the service. Due to the limited number of established facilities, a standardized pricing structure is largely absent. Instead, costs are often negotiated on a case-by-case basis, taking into account direct material expenses, labor, and overhead. The prevailing economic conditions and exchange rates of the South Sudanese Pound (SSP) significantly impact the final pricing.

Service Type (Illustrative)Estimated Price Range (SSP)Notes
Basic DNA/RNA Extraction (per sample)15,000 - 30,000Includes reagents and basic lab processing. Price can vary based on sample type (blood, tissue, plant).
PCR-based Genotyping (e.g., STR profiling, single-locus SNP analysis) (per sample)20,000 - 40,000Covers reagents, PCR setup, and basic gel or capillary electrophoresis. Complex panels will be higher.
Targeted Gene Sequencing (e.g., Sanger sequencing of a single gene region) (per sample)40,000 - 80,000Includes DNA extraction, PCR amplification, sequencing, and basic analysis. More genes/regions increase cost.
Library Preparation for Next-Generation Sequencing (NGS) (per sample)70,000 - 150,000+Highly dependent on the library preparation kit and the target application (e.g., exome, targeted panel).
NGS Sequencing (e.g., 100 bp paired-end run on a mid-throughput sequencer) (per run, cost per sample will vary)500,000 - 1,500,000+ (for the run)This is a highly variable cost. The actual per-sample cost depends on multiplexing and sequencing depth. Includes sequencer consumables.
Basic Bioinformatic Analysis (e.g., variant calling, simple read mapping) (per project)100,000 - 300,000+Depends on the size of the dataset and the complexity of the analysis. Can be a significant additional cost.

Key Pricing Factors for Genomics Core Facilities in South Sudan

  • Reagent and Consumable Costs: Primarily driven by import costs, customs duties, and local supplier markups for specialized reagents, kits, and consumables (e.g., DNA/RNA extraction kits, library preparation kits, sequencing reagents).
  • Equipment Acquisition and Maintenance: The high initial investment in advanced genomic equipment (sequencers, PCR machines, centrifuges, etc.) and the ongoing costs of maintenance, calibration, and potential repair in a remote location contribute significantly.
  • Personnel Costs: Salaries for highly skilled personnel, including molecular biologists, bioinformaticians, and lab technicians, are a major component, especially given the limited local talent pool and the need for specialized training.
  • Infrastructure and Utilities: Costs associated with maintaining a suitable laboratory environment (e.g., electricity, reliable water supply, climate control) in South Sudan can be substantial.
  • Sample Processing Volume: Larger sample volumes may allow for economies of scale, potentially reducing the per-sample cost.
  • Type of Genomic Assay/Service: Different assays have vastly different reagent and labor requirements. For example, whole-genome sequencing is considerably more expensive than targeted gene sequencing or basic PCR genotyping.
  • Bioinformatics Analysis: The complexity and depth of bioinformatic analysis required (e.g., variant calling, transcriptome analysis, population genetics studies) will impact costs due to the specialized expertise and computational resources needed.
  • Turnaround Time (TAT): Expedited services often come with a premium.
  • Institutional Overhead and Profit Margins: Academic institutions or private entities will factor in their operational overhead and desired profit margins.
  • Geographic Location within South Sudan: While less of a direct pricing factor for the service itself, logistical challenges and transportation costs for sample delivery and reagent acquisition can indirectly influence overall service costs if the facility is in a particularly remote area.

Affordable Genomics Core Facilities Options

Affordable genomics core facilities are crucial for researchers to access cutting-edge technologies without prohibitive costs. Many core facilities offer various cost-saving strategies and value bundles to make their services more accessible. Understanding these options can significantly reduce research expenses and expand the scope of scientific inquiry. Value bundles typically involve combining multiple services or consumables at a discounted rate compared to purchasing them individually. Cost-saving strategies encompass a range of approaches, from bulk purchasing and shared resources to optimized experimental design and data analysis pipelines.

Service/Bundle TypeDescriptionPotential SavingsConsiderations
Standard Sequencing BundleIncludes library preparation (e.g., Illumina TruSeq) and a set number of high-throughput sequencing lanes (e.g., NovaSeq).10-20% discount compared to individual service costs.Ideal for large-scale projects like whole-genome or exome sequencing.
Targeted Sequencing PackageCombines probe design, target enrichment, library preparation, and sequencing for specific gene panels or regions.Up to 15% savings on focused genomic analyses.Cost-effective for studying specific genes or mutations.
Single-Cell RNA-Seq BundleIntegrates cell isolation, library preparation, and sequencing for thousands to millions of individual cells.Economical for high-resolution cellular profiling.Requires specialized expertise and potentially bioinformatics support.
Microbiome Sequencing PackageOften includes DNA extraction, 16S rRNA gene or shotgun metagenomic sequencing, and basic bioinformatics analysis.Streamlined workflow for microbial community studies.Bundle may vary in included analysis depth.
Genotyping and SNP Array ServicesBundled services for high-throughput genotyping using microarrays or targeted sequencing approaches.Significant cost reduction for large-scale genotyping studies.Choice of array type or targeted panel is important.
Custom Panel Design & SequencingCombines the design of custom capture probes with library preparation and sequencing for user-defined targets.Can be more cost-effective than commercial panels for highly specific research needs.Requires significant user input for target selection.

Cost-Saving Strategies for Genomics Core Facilities

  • Value Bundles: Core facilities often package related services together, such as library preparation and sequencing, at a reduced price. These bundles can be particularly beneficial for common workflows.
  • Bulk Discounts: Inquire about discounts for large sample submissions or repeat service requests. Many facilities offer tiered pricing based on volume.
  • Consumables Management: Explore options for the core facility to manage and purchase common reagents in bulk, passing on savings to users.
  • Internal vs. External Pricing: Some core facilities offer different pricing structures for internal researchers versus external collaborators.
  • Service Level Agreements (SLAs): For high-volume users or specific projects, negotiating SLAs can provide predictable pricing and dedicated support.
  • Training and DIY Options: Some facilities offer training on specific equipment or techniques, allowing researchers to perform certain steps themselves, reducing service fees.
  • Data Storage and Analysis Packages: Look for bundled solutions that include data storage, basic bioinformatics analysis, and potentially cloud computing credits.
  • Collaborative Purchasing: If your institution has multiple research groups using similar genomics services, consider pooling resources for bulk purchases of reagents or services.
  • Prioritization and Turnaround Time Options: Flexible turnaround times can sometimes be cheaper. If your project isn't time-sensitive, inquire about lower-cost options with longer processing times.
  • Grant Application Support: Many core facilities can assist with grant applications by providing detailed quotes and descriptions of services, which can be crucial for securing funding.
  • Early Access Programs: Some facilities might offer discounted access to new technologies or services for early adopters to gather feedback and usage data.

Verified Providers In South Sudan

Ensuring access to quality healthcare is paramount in South Sudan, where reliable and credentialed medical providers are essential for community well-being. Franance Health stands out as a beacon of trust, consistently demonstrating a commitment to high standards and ethical practices. Their dedication to verifiable credentials means patients can have confidence in the expertise and qualifications of their healthcare professionals. This commitment translates into a superior patient experience, characterized by effective treatment, patient safety, and a compassionate approach.

Provider TypeKey CredentialsFranance Health's Commitment
General PractitionersMedical Degree (MBBS/MD), Valid Medical License, Practicing CertificateVerified academic records, background checks, and ongoing professional development.
Specialist Doctors (e.g., Surgeons, Pediatricians, Gynecologists)Medical Degree, Specialization Certification, Fellowship (where applicable), Valid Medical LicenseConfirmation of specialized training from accredited institutions, peer reviews, and continuous medical education.
Nurses (Registered Nurses, Midwives)Nursing Diploma/Degree, Nursing Council Registration, Practicing LicenseVerification of nursing school credentials, professional body membership, and practical experience assessments.
PharmacistsPharmacy Degree, Pharmacy Council Registration, License to PracticeEnsuring dispensing accuracy, drug interaction knowledge, and adherence to pharmaceutical regulations.

Why Franance Health is the Best Choice:

  • Verifiable Credentials: Franance Health rigorously vets all their healthcare professionals, ensuring all licenses, certifications, and educational backgrounds are up-to-date and legitimate.
  • Experienced Professionals: Their team comprises highly skilled and experienced doctors, nurses, and specialists with a deep understanding of local health challenges and global best practices.
  • Patient-Centered Care: Franance Health prioritizes patient comfort, dignity, and informed decision-making, fostering a trusting relationship between providers and patients.
  • Comprehensive Services: They offer a wide range of medical services, from primary care to specialized treatments, addressing diverse healthcare needs within the community.
  • Commitment to Quality: Continuous professional development and adherence to strict quality control measures ensure the delivery of excellent healthcare outcomes.

Scope Of Work For Genomics Core Facilities

This Scope of Work (SOW) outlines the technical deliverables and standard specifications for services provided by Genomics Core Facilities. It serves as a framework for understanding the capabilities and expectations of the core, ensuring consistent quality and efficient utilization of resources for research projects.

Service AreaTechnical DeliverablesStandard Specifications/Requirements
Next-Generation Sequencing (NGS) ServicesRaw sequencing data (FASTQ files)Sequencing platform: Illumina NovaSeq/HiSeq/MiSeq (or equivalent)Read length: Customizable (e.g., 50 bp, 100 bp, 150 bp paired-end)Data quality control reports (e.g., FastQC, MultiQC)Alignment reports (BAM/SAM files) to a reference genomeVariant calling reports (VCF files) where applicableLibrary preparation methods: Whole genome, exome, RNA-Seq (poly-A selection or ribo-depletion), ChIP-Seq, ATAC-Seq, etc.Minimum sequencing depth: Project-dependent (e.g., 30x for exomes, 50M-100M reads for RNA-Seq)Reagent kits: Illumina-compatible library preparation kits
Genotyping and Genotyping ServicesGenotype data (e.g., PLINK format, VCF)Genotyping platform: Illumina iScan, Affymetrix GeneChip (or equivalent)SNP array data processing and quality controlMendelian error checks, call rate assessmentAllele frequency reportingParent-offspring relationships analysis (optional)Assay design and custom panel creation (upon request)Sample throughput: Scalable based on project needs
Gene Expression AnalysisNormalized gene expression values (e.g., TPM, FPKM, normalized counts)Microarray data analysis: QC, normalization (e.g., RMA, GCRMA), differential gene expression analysisRNA-Seq analysis: Alignment, quantification, differential gene expression analysis (e.g., DESeq2, edgeR)Data visualization: Heatmaps, volcano plots, principal component analysis (PCA)Gene set enrichment analysis (GSEA)Specific transcript quantification (e.g., isoform analysis)Required sample input: DNA-free RNA (e.g., 100 ng - 1 µg for RNA-Seq)
Epigenomics ServicesChIP-Seq: Peak calling files (BED format), differential peak analysis, motif enrichment analysisATAC-Seq: Peak calling files (BED format), differential accessibility analysisBisulfite sequencing: Methylation calls (BEDGraph, VCF), differential methylation analysisInput DNA: Typically 5-10 ng for ChIP/ATAC-Seq, 1 µg for bisulfite sequencingAntibody validation and optimization (for ChIP-Seq)Bioinformatics pipeline: Standardized pipelines for each epigenomic assay
Bioinformatics and Data Analysis SupportCustomized analysis pipelinesData QC and preprocessingStatistical analysis and interpretationData visualization and report generationDatabase integration and queryingSoftware: R, Python, Bioconductor, Galaxy, etc.Computational resources: Access to high-performance computing (HPC) clustersData storage and management: Secure storage solutions, data archiving policies

Key Service Areas

  • Next-Generation Sequencing (NGS) Services
  • Genotyping and Genotyping Services
  • Gene Expression Analysis
  • Epigenomics Services
  • Bioinformatics and Data Analysis Support

Service Level Agreement For Genomics Core Facilities

This Service Level Agreement (SLA) outlines the guaranteed response times and uptime for services provided by the Genomics Core Facility. This SLA is designed to ensure reliable and efficient access to our genomic services for all users.

Service CategoryResponse Time Guarantee (Business Hours)Uptime GuaranteeNotes
Sequencing Services (Sample Submission & Initial QC)2 business days for initial confirmation and library QC status95% UptimeExcludes scheduled maintenance or unforeseen hardware failures. Uptime refers to the availability of sequencing instruments and associated workflows.
Genotyping Services (Sample Submission & Initial QC)2 business days for initial confirmation and library QC status95% UptimeExcludes scheduled maintenance or unforeseen hardware failures. Uptime refers to the availability of genotyping instruments and associated workflows.
Gene Expression Analysis (Sample Submission & Initial QC)2 business days for initial confirmation and library QC status95% UptimeExcludes scheduled maintenance or unforeseen hardware failures. Uptime refers to the availability of expression analysis instruments and associated workflows.
Bioinformatics Support (Data Analysis Requests)5 business days for initial assessment and project scope definition. Further timeline defined per project.N/AResponse time applies to initial contact and scope definition. Actual analysis timelines will be project-specific and communicated during the scoping phase.
Sample Preparation and QC1 business day for confirmation of sample receipt and initial quality assessment.98% UptimeUptime refers to the availability of robotic liquid handlers, PCR machines, and QC instruments.
General Inquiries & Technical Support4 business hours for initial acknowledgment. Resolution time will vary based on complexity.N/AApplies to email and in-person inquiries during business hours.

Scope of Services Covered

  • Sequencing Services (e.g., Illumina, PacBio, Nanopore)
  • Genotyping Services (e.g., SNP arrays, ddRADseq)
  • Gene Expression Analysis (e.g., RNA-Seq, qPCR)
  • Bioinformatics Support (e.g., data analysis, interpretation)
  • Sample Preparation and QC
In-Depth Guidance

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