Verified Service Provider in Ivory Coast
Cell Culture Suites in Ivory Coast
Engineering Excellence & Technical Support
Cell Culture Suites solutions for Research & Discovery (R&D). High-standard technical execution following OEM protocols and local regulatory frameworks.
State-of-the-Art Aseptic Processing Capabilities
Our cell culture suites in Ivory Coast are equipped with advanced laminar flow hoods, isolators, and sterile transfer systems, ensuring unparalleled sterility and minimizing contamination risks for sensitive cell cultures.
Advanced Bioreactor Technology for Scalable Production
Leveraging cutting-edge bioreactor systems, we offer scalable cell culture solutions, from research-grade volumes to GMP-compliant production, enabling efficient and consistent generation of therapeutic cells and biologics.
Comprehensive In-Process Quality Control & Monitoring
Integrated real-time monitoring systems for critical parameters (temperature, pH, dissolved oxygen) and rigorous in-process QC testing (viability, cell count, purity) are fundamental to our cell culture suites, guaranteeing the integrity and quality of every batch.
What Is Cell Culture Suites In Ivory Coast?
Cell culture suites in Ivory Coast refer to specialized, controlled laboratory environments designed for the growth and maintenance of cell lines, tissues, or microorganisms under aseptic conditions. These facilities are critical for a wide range of biological research, diagnostics, and biopharmaceutical production. They are characterized by stringent environmental controls (temperature, humidity, CO2 levels), sophisticated air filtration systems (HEPA filters), and the provision of sterile consumables and equipment necessary to prevent contamination. The primary objective is to create an environment that mimics the physiological conditions required for cellular viability and proliferation, while simultaneously ensuring the sterility and integrity of the cultures.
| Who Needs Cell Culture Suites? | Typical Use Cases | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Research institutions (universities, government research centers) conducting basic biological and biomedical research. | Pharmaceutical and biotechnology companies involved in drug discovery, development, and manufacturing. | Diagnostic laboratories performing various biological assays and tests. | Hospitals and clinical research centers for translational research and specialized diagnostics. | Agricultural research facilities for plant tissue culture and microbial studies. | Companies involved in the production of biologics, vaccines, and recombinant proteins. | ||||
| Drug screening and efficacy testing. | Toxicity studies (in vitro). | Development of monoclonal antibodies and therapeutic proteins. | Vaccine production and testing. | Stem cell research and regenerative medicine. | Cancer research and development of targeted therapies. | Infectious disease research (viral, bacterial, parasitic). | Genomic and proteomic studies. | Development of cell-based assays for diagnostics. | Plant propagation and genetic modification (in agricultural contexts). |
Key Components and Services of Cell Culture Suites:
- Sterile workspace: Biosafety cabinets (BSCs) or laminar flow hoods providing a sterile working area.
- Incubators: Controlled environments for maintaining optimal temperature, humidity, and CO2 levels.
- Media preparation areas: Facilities for preparing and sterilizing cell culture media and reagents.
- Reagent storage: Refrigerated and frozen storage for media, sera, antibiotics, and other supplements.
- Microscopy: Access to inverted microscopes for cell observation and analysis.
- Centrifugation: Equipment for cell separation and manipulation.
- Autoclaving: Sterilization of reusable equipment and consumables.
- Waste disposal: Protocols for the safe and sterile disposal of biohazardous waste.
- Qualified personnel: Trained technicians and researchers proficient in aseptic techniques and cell culture methodologies.
- Quality control: Procedures for monitoring cell viability, purity, and identity.
Who Needs Cell Culture Suites In Ivory Coast?
Cell culture suites are specialized laboratory facilities designed for the sterile growth and manipulation of living cells outside their natural environment. These sophisticated environments require precise control over temperature, humidity, CO2 levels, and a sterile atmosphere to prevent contamination. In Ivory Coast, as in many developing nations, advancements in biotechnology, medical research, and pharmaceuticals are increasingly reliant on these capabilities. Therefore, understanding who specifically needs and would benefit from cell culture suites is crucial for investment, resource allocation, and strategic planning. The demand is driven by entities engaged in cutting-edge scientific endeavors, aiming to improve public health, develop new diagnostics and therapeutics, and advance scientific knowledge.
| Department/Sector | Specific Needs and Applications | Key Benefits for Ivory Coast |
|---|---|---|
| Medical Research (e.g., Infectious Diseases, Oncology, Immunology) | Isolation and characterization of pathogens, drug efficacy testing, cancer cell line studies, immune cell function analysis. | Improved understanding and treatment of prevalent diseases like malaria, HIV, and neglected tropical diseases; development of targeted therapies. |
| Biotechnology and Pharmaceutical Development | Production of recombinant proteins (e.g., therapeutic antibodies), cell-based assays for drug screening, vaccine development and manufacturing. | Local production of essential medicines and vaccines, reduced reliance on imports, creation of high-skilled jobs, and potential for export. |
| Diagnostic Laboratories (Public and Private) | Virus isolation and identification, antimicrobial susceptibility testing for bacteria, cellular diagnostics for various conditions. | Faster and more accurate diagnosis of diseases, enabling timely and appropriate treatment, contributing to disease control efforts. |
| Regenerative Medicine and Tissue Engineering | Expansion of stem cells for therapeutic applications, development of engineered tissues for transplantation or research. | Potential for advanced medical treatments, addressing unmet medical needs, and positioning Ivory Coast as a regional leader in this field. |
| Veterinary Services and Animal Health | Culturing of animal viruses and bacteria, development of veterinary vaccines, diagnostic testing for livestock diseases. | Protection of the agricultural sector, prevention of zoonotic disease transmission, and improved food security. |
| Environmental Science and Biotechnology | Bioremediation research, ecotoxicology studies, microbial strain development for industrial purposes. | Solutions for environmental challenges, sustainable industrial practices, and potential for bio-based product development. |
Target Customers and Departments for Cell Culture Suites in Ivory Coast:
- {"title":"Academic and Research Institutions","description":"Universities and dedicated research centers are at the forefront of scientific discovery and require cell culture facilities for fundamental research in biology, medicine, and related fields. This includes investigating disease mechanisms, developing new drug targets, and exploring cellular processes."}
- {"title":"Hospitals and Clinical Laboratories","description":"Hospitals, particularly those with specialized departments, can utilize cell culture for diagnostic purposes (e.g., testing drug sensitivity of pathogens), for autologous cell therapies (e.g., regenerative medicine), and for research into local diseases. This can lead to more personalized and effective patient care."}
- {"title":"Pharmaceutical and Biotechnology Companies","description":"Companies involved in drug discovery, development, and manufacturing of biological products, vaccines, and diagnostics. Cell culture is essential for screening potential drug candidates, producing recombinant proteins, and conducting quality control."}
- {"title":"Government Health Agencies and Public Health Laboratories","description":"Organizations responsible for monitoring and controlling infectious diseases, developing public health strategies, and producing essential vaccines or diagnostics. Cell culture capabilities can enhance disease surveillance, vaccine production, and the development of rapid diagnostic tests for prevalent diseases in Ivory Coast."}
- {"title":"Veterinary Research and Diagnostic Centers","description":"Institutions focused on animal health, livestock development, and the control of zoonotic diseases. Cell culture is vital for studying animal pathogens, developing veterinary vaccines, and diagnosing animal diseases that can impact agriculture and public health."}
- {"title":"Environmental Research and Monitoring Facilities","description":"Organizations studying the impact of environmental factors on biological systems or using biological agents for bioremediation. Cell culture can be used to assess the toxicity of pollutants or to cultivate microorganisms for industrial applications."}
Cell Culture Suites Process In Ivory Coast
This document outlines the typical workflow for establishing and operating cell culture suites in Ivory Coast, from the initial inquiry stage to the final execution of research or production activities. The process emphasizes regulatory compliance, quality control, and efficient resource management within the Ivorian context.
| Stage | Description | Key Activities | Responsible Parties | Typical Timeline (Indicative) |
|---|---|---|---|---|
| Initial contact to understand the client's requirements for cell culture facilities. | Define scope of work, budget, desired capacity, type of cell cultures (e.g., mammalian, microbial), research vs. production, specific equipment needs. | Client/Research Institution, Potential Service Provider/Consultant | 1-2 Weeks |
| Identifying and planning the physical space for the cell culture suites. | Site survey, space planning, architectural and engineering design, HVAC, biosafety level (BSL) considerations, utility requirements (power, water, gas), waste management strategy. | Client/Research Institution, Architects, Engineers, Biosafety Consultants | 4-8 Weeks |
| Securing necessary permits and adhering to Ivorian biosafety and environmental regulations. | Submission of design plans and risk assessments to relevant ministries (e.g., Ministry of Health, Ministry of Environment), obtaining building permits, biosafety permits, waste disposal permits. | Client/Research Institution, Regulatory Bodies (e.g., ANSP - Agence Nationale de la Sécurité Sanitaire) | 8-16 Weeks (can be highly variable) |
| Acquiring and setting up all necessary equipment and infrastructure. | Equipment sourcing (incubators, biosafety cabinets, microscopes, centrifuges, refrigerators/freezers), material procurement, specialized construction (e.g., cleanroom finishes), installation of utilities, IT infrastructure. | Client/Research Institution, Equipment Suppliers, Contractors, IT Specialists | 12-24 Weeks |
| Ensuring the facility and equipment meet specified performance standards and are fit for purpose. | Installation Qualification (IQ), Operational Qualification (OQ), Performance Qualification (PQ) for equipment. Environmental monitoring validation. Sterilization/decontamination validation. SOP development and initial training. | Client/Research Institution, Validation Engineers, Quality Assurance Team | 6-10 Weeks |
| Equipping personnel with the necessary skills and knowledge for cell culture operations. | Training on aseptic techniques, equipment operation, SOPs, biosafety protocols, emergency procedures, data recording, quality control procedures. | Client/Research Institution, Experienced Personnel, External Trainers | 4-6 Weeks (ongoing) |
| Beginning routine cell culture activities within the validated suites. | Initiation of cell culture experiments/production, adherence to SOPs, data collection and analysis, regular reporting. | Research Staff, Production Technicians, Supervisors | Ongoing |
| Continuous oversight to ensure optimal performance and safety of the facility and equipment. | Regular environmental monitoring (temperature, humidity, CO2 levels), equipment calibration and preventative maintenance, media preparation, inventory management, waste disposal. | Facility Management, Maintenance Technicians, Cell Culture Staff | Ongoing |
| Implementing systems to ensure the reliability, reproducibility, and safety of cell culture processes. | Internal audits, deviation management, change control, corrective and preventive actions (CAPA), record-keeping, adherence to Good Laboratory Practices (GLP) or Good Manufacturing Practices (GMP) as applicable. | Quality Assurance Department, Management | Ongoing |
| Safely shutting down and dismantling the cell culture suites. | Decontamination procedures, waste disposal, equipment removal, site restoration, final regulatory reporting. | Client/Research Institution, Specialized Decommissioning Companies, Regulatory Bodies | 2-4 Weeks |
Cell Culture Suites Process Workflow
- Inquiry and Needs Assessment
- Site Selection and Design
- Regulatory Approvals and Permitting
- Procurement and Installation
- Validation and Qualification
- Staff Training and Development
- Operational Commencement
- Routine Monitoring and Maintenance
- Quality Assurance and Control
- Decommissioning (if applicable)
Cell Culture Suites Cost In Ivory Coast
The cost of cell culture suites in Ivory Coast can vary significantly based on several key factors, making it challenging to provide a single definitive price. These costs are typically quoted in West African CFA Franc (XOF). The primary drivers influencing the price include the size and complexity of the suite, the level of sophistication of the equipment included, the required certifications and compliance standards (e.g., GMP, ISO), and the specific service provider or manufacturer engaged. Labor and installation costs also play a crucial role, especially for custom-designed facilities. Ongoing maintenance and validation services can add to the overall investment. Generally, a basic, smaller cell culture room might start at a lower price point, while a fully equipped, larger, and highly compliant biosafety level (BSL) rated suite will command a significantly higher price.
| Suite Type / Scope | Estimated Cost Range (XOF) | Notes |
|---|---|---|
| Basic Cell Culture Room (e.g., ~15-20 sqm, BSL-2 basic features) | 15,000,000 - 40,000,000 | Includes essential BSC, incubator, basic HVAC, standard finishes. Primarily for educational or early-stage research. |
| Standard Cell Culture Suite (e.g., ~30-50 sqm, BSL-2 compliant) | 40,000,000 - 100,000,000 | More robust HVAC, advanced BSCs, multiple incubators, centrifuges, water purification, and basic validation. Suitable for most research labs and smaller biotech. |
| Advanced/GMP-Compliant Cell Culture Suite (e.g., ~50-100+ sqm, BSL-2/3 features) | 100,000,000 - 300,000,000+ | High-grade materials, sophisticated multi-zone HVAC, multiple BSL-rated cabinets, Class A/B cleanroom standards, full validation, automation, and potentially specialized equipment for bioprocessing. For pharmaceutical, diagnostics, or advanced biotech. |
| Minor Upgrades/Retrofitting of Existing Space | 5,000,000 - 25,000,000 | Adding a single biosafety cabinet, upgrading HVAC for a small lab, or improving cleanroom conditions. Highly variable based on scope. |
Factors Affecting Cell Culture Suite Costs in Ivory Coast:
- Suite Size and Layout: Larger, multi-room facilities or those with specialized sections (e.g., sterile processing, clean rooms, dedicated equipment areas) will be more expensive.
- Level of Cleanliness and Air Filtration (HVAC): The required air changes per hour (ACH), HEPA filtration efficiency, and positive/negative pressure differentials for different zones directly impact HVAC system costs.
- Biosafety Level (BSL) Requirements: Higher BSL ratings (e.g., BSL-2, BSL-3) necessitate more stringent containment measures, specialized equipment, and safety features, leading to higher costs.
- Included Equipment and Instrumentation: The type and quantity of essential cell culture equipment such as biosafety cabinets (BSCs), incubators (CO2, tri-gas), centrifuges, microscopes, laminar flow hoods, autoclaves, and ultrapure water systems will significantly influence the total cost.
- Materials and Finishes: The choice of durable, easy-to-clean, and sterile-compatible materials for walls, floors, and ceilings (e.g., epoxy coatings, stainless steel) affects the budget.
- Electrical and Plumbing Infrastructure: Upgrades or new installations for specialized power requirements, emergency power backup, and specific plumbing needs (e.g., dedicated waste disposal) add to the expense.
- Automation and Control Systems: Integration of building management systems (BMS), environmental monitoring, and automated controls for HVAC, lighting, and access can increase initial investment.
- Certification and Validation: Costs associated with design review, construction validation, performance qualification (PQ), and operational qualification (OQ) to meet regulatory standards are crucial.
- Installation and Commissioning: The complexity of the site, geographical location within Ivory Coast, and the extent of on-site assembly and testing will influence labor costs.
- Service and Maintenance Contracts: Long-term service agreements for equipment and facility upkeep can be a significant ongoing expense.
- Supplier/Manufacturer Reputation and Origin: Prices can vary between local Ivorian providers and international suppliers, with the latter often carrying higher price tags due to import duties and logistics.
Affordable Cell Culture Suites Options
Acquiring cell culture suites can be a significant investment. Fortunately, there are various affordable options available, focusing on value bundles and strategic cost-saving measures. This guide explores how to secure essential cell culture facilities without breaking the bank. We'll delve into understanding what constitutes a value bundle in this context and outline practical strategies to reduce overall expenditure.
| Cost-Saving Strategy | Description | Potential Savings Level |
|---|---|---|
| Value Bundles | Purchasing a pre-selected package of essential cell culture equipment (e.g., biosafety cabinet, incubator, microscope) from a single supplier at a discounted price compared to individual purchases. | Moderate to High |
| Refurbished Equipment | Buying certified pre-owned biosafety cabinets, incubators, centrifuges, and other lab essentials from specialized vendors. Often comes with a warranty. | High |
| Modular/Prefabricated Rooms | Utilizing pre-built, self-contained cell culture rooms that require minimal on-site construction. Reduces labor and material costs associated with traditional builds. | Moderate to High |
| Shared Facility Access | Institutions or departments pooling resources to create a centralized cell culture facility, allowing multiple users to share equipment and space. | Very High (for individual users) |
| Leasing vs. Buying Equipment | Exploring leasing options for expensive equipment, especially for short-term projects or when budget flexibility is paramount. Can offer lower upfront costs. | Moderate |
| Negotiating Bulk Discounts | If purchasing multiple items or planning for future expansions, negotiating volume discounts with suppliers can lead to significant savings. | Moderate |
| DIY Customization (where appropriate) | For non-critical aspects, consider simple DIY solutions for shelving or storage to reduce costs, while ensuring all safety and sterility requirements are met for core equipment. | Low to Moderate |
Key Components of Affordable Cell Culture Suites
- Modular Design: Opting for modular or pre-fabricated cell culture rooms can significantly reduce construction time and costs compared to traditional builds. These units often come with integrated HVAC, lighting, and basic utility connections, streamlining the setup process.
- Refurbished Equipment: Investing in high-quality, certified refurbished biosafety cabinets, incubators, centrifuges, and microscopes can offer substantial savings. Reputable suppliers often provide warranties, ensuring the reliability of these pre-owned instruments.
- Bundled Packages: Many manufacturers and suppliers offer "value bundles" that combine essential equipment and furniture at a discounted price. These packages are designed to equip a basic cell culture lab efficiently, minimizing the need to source individual items.
- Shared Facility Models: For smaller research groups or institutions with limited budgets, exploring shared cell culture facilities can be an extremely cost-effective solution. This model allows multiple users to access and share expensive equipment and infrastructure, dividing operational costs.
- Phased Implementation: Instead of building a fully equipped suite at once, consider a phased approach. Start with essential equipment and expand as your research needs and budget grow. This allows for better financial planning and avoids upfront over-expenditure.
- Energy-Efficient Solutions: Incorporating energy-efficient lighting, HVAC systems, and equipment can lead to long-term operational cost savings. While the initial investment might be slightly higher, the reduced utility bills will contribute to affordability over time.
Verified Providers In Ivory Coast
Ensuring access to quality healthcare is paramount, and in Ivory Coast, identifying verified providers is crucial for patients seeking reliable and trustworthy medical services. Franance Health has emerged as a leader in this space, setting a benchmark for excellence through its rigorous credentialing process and commitment to patient well-being. This document outlines why Franance Health credentials represent the best choice for individuals and families in Ivory Coast.
| Credentialing Aspect | Franance Health Standard | Benefit to Patients |
|---|---|---|
| Medical Licenses | Active and valid licenses from recognized regulatory bodies are mandatory. | Guarantees legal and ethical practice. |
| Educational Background | Verification of degrees and specialized training from accredited institutions. | Ensures a strong foundation of medical knowledge. |
| Professional Experience | Thorough review of past work history, including hospital affiliations and practice duration. | Indicates practical expertise and established credibility. |
| Continuing Medical Education (CME) | Proof of ongoing participation in CME programs to stay abreast of medical advancements. | Ensures patients receive current and evidence-based treatments. |
| Peer Reviews & Reputation | Consideration of peer reviews and professional reputation within the medical community. | Provides an additional layer of quality assurance. |
| Ethical Conduct | Adherence to a strict code of ethics and professional conduct. | Protects patients from malpractice and unethical practices. |
Key Reasons to Trust Franance Health Credentials:
- Stringent Verification Processes: Franance Health employs a multi-faceted approach to vet healthcare providers, ensuring they meet the highest standards of professional competence and ethical conduct. This includes verifying medical licenses, educational qualifications, and professional experience.
- Commitment to Quality Care: Beyond basic credentials, Franance Health assesses providers based on their dedication to patient-centered care, adherence to best practices, and continuous professional development. This ensures patients receive up-to-date and effective treatments.
- Patient Safety Focus: The credentialing process at Franance Health prioritizes patient safety above all else. Providers are evaluated for their adherence to safety protocols, infection control measures, and their ability to manage emergencies effectively.
- Transparency and Accountability: Franance Health maintains a transparent system, allowing patients to have confidence in the providers they choose. Each credentialed provider is held accountable to a code of conduct, fostering trust and reliability.
- Access to a Network of Excellence: By choosing a Franance Health credentialed provider, patients gain access to a curated network of highly skilled and reputable medical professionals across various specialties, simplifying the process of finding the right care.
- Enhanced Patient Experience: The assurance of receiving care from a verified provider contributes significantly to a positive patient experience. Knowing that a provider has met rigorous standards reduces anxiety and promotes a sense of security.
Scope Of Work For Cell Culture Suites
This Scope of Work (SOW) outlines the technical deliverables and standard specifications for the design, construction, and commissioning of Cell Culture Suites. The objective is to establish state-of-the-art facilities that meet stringent biosafety, environmental control, and operational requirements for advanced cell culture research and development.
| Category | Specification/Requirement | Details/Notes |
|---|---|---|
| Biosafety Level (BSL) | BSL-2 or BSL-3 as per CDC/WHO guidelines | Dependent on the specific cell lines and experiments to be conducted. Shall include appropriate containment features. |
| HVAC System | HEPA Filtration (supply and exhaust) | Minimum MERV 17 for supply, HEPA for exhaust. Redundant fans for critical areas. |
| Airflow Control | Positive/Negative pressure differentials | Specific gradients required to prevent cross-contamination and maintain containment. Monitored and alarmed. |
| Room Integrity | Airtight construction | Leak-tight doors, penetrations, and sealed surfaces. Pressure decay testing required. |
| Sterilization/Decontamination | Autoclave (on-site or easily accessible) | Appropriate capacity and cycle validation for biohazardous waste and materials. |
| Surface Finishes | Smooth, non-porous, and chemical-resistant | Epoxy or equivalent seamless flooring, wall coatings, and ceiling materials. |
| Lighting | Uniform and sufficient illumination | Minimum 500 lux at benchtop level. Consider UV-C disinfection options. |
| Electrical Systems | Uninterruptible Power Supply (UPS) for critical equipment | Adequate outlets, emergency power provisions for essential systems. |
| Plumbing | Dedicated sink with hands-free operation | Emergency eyewash and shower stations. Appropriate drainage and waste collection. |
| Waste Management | Segregated waste streams | Clearly labeled containers for biohazardous, sharps, and general waste. Autoclave for biohazard inactivation. |
| Environmental Monitoring | Temperature, humidity, pressure differentials | Continuous monitoring with data logging and alarm systems. |
| Access Control | Biometric or card-based access | Restricted access to authorized personnel only. Audit trails. |
| Communication Systems | Intercom and emergency alert system | Essential for communication within containment areas. |
| Biosafety Cabinets (BSCs) | Class II Type A2 or B2 as per NSF/ANSI 49 | Appropriate number and placement based on workflow and biosafety requirements. |
| Incubators | CO2 incubators with precise control | Redundant units recommended for critical cell lines. |
| Centrifuges | Biological safety centrifuges with sealed rotors | Appropriate speed and capacity. |
Technical Deliverables
- Detailed Design Drawings (Architectural, Mechanical, Electrical, Plumbing, HVAC, Biosafety Systems)
- Equipment Specifications and Procurement Packages
- Commissioning Plan and Reports (IQ, OQ, PQ)
- Standard Operating Procedures (SOPs) for Facility Operation and Maintenance
- As-Built Drawings
- Training Manuals for Facility Staff
- Validation Documentation for all Critical Systems
- Waste Management and Decontamination Protocols
Service Level Agreement For Cell Culture Suites
This Service Level Agreement (SLA) outlines the guaranteed response times and uptime for the Cell Culture Suites. It is designed to ensure reliable and consistent performance for critical research operations.
| Service Component | Response Time Guarantee (Business Hours) | Resolution Time Guarantee (Business Hours) | Uptime Guarantee (Monthly) |
|---|---|---|---|
| Environmental Controls (Temperature, Humidity, CO2) | 1 Hour | 4 Hours | 99.5% |
| Incubators | 1 Hour | 4 Hours | 99.0% |
| Biological Safety Cabinets (HEPA Filter Integrity Verified) | 2 Hours | 8 Hours | 99.0% |
| General Facility Power and Lighting | 2 Hours | 6 Hours | 99.8% |
| Access Control Systems | 1 Hour | 4 Hours | 99.5% |
Key Definitions
- Cell Culture Suite: A dedicated, environmentally controlled laboratory space designed for sterile cell culture work.
- Downtime: Any period during which a Cell Culture Suite is unavailable for use due to equipment malfunction, environmental control failure, or scheduled maintenance that exceeds the permitted window.
- Response Time: The maximum time allowed for a designated technician or service provider to acknowledge and begin addressing a reported issue.
- Resolution Time: The maximum time allowed to restore a Cell Culture Suite to its intended operational state following a reported issue.
- Uptime Guarantee: The minimum percentage of time a Cell Culture Suite is expected to be available for use within a given period.
In-Depth Guidance
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