
Genomics Core Facilities in Burkina Faso
Engineering Excellence & Technical Support
Genomics Core Facilities solutions for Research & Discovery (R&D). High-standard technical execution following OEM protocols and local regulatory frameworks.
Advanced DNA Sequencing Services
Our state-of-the-art genomics core facility provides high-throughput DNA sequencing (e.g., Illumina NovaSeq) for a wide range of applications, including whole-genome sequencing, exome sequencing, and targeted sequencing. We enable researchers to uncover genetic variations crucial for understanding disease resistance, agricultural traits, and biodiversity in Burkina Faso's unique ecosystems.
Next-Generation Gene Expression Analysis
Leveraging cutting-edge technologies like RNA-Seq and qPCR, our facility offers comprehensive gene expression profiling. This allows scientists to study cellular responses to environmental factors, identify key genes involved in crop development and pest resistance, and advance our understanding of host-pathogen interactions relevant to public health in the region.
CRISPR-Cas9 Gene Editing Capabilities
We empower researchers with advanced CRISPR-Cas9 gene editing services, enabling precise modification of genomes in model organisms and target crops. This capability is instrumental for developing disease-resistant varieties of staple crops, studying genetic mechanisms of agricultural productivity, and contributing to sustainable food security initiatives in Burkina Faso.
What Is Genomics Core Facilities In Burkina Faso?
Genomics Core Facilities in Burkina Faso represent centralized, shared infrastructure and expert services dedicated to enabling advanced genomic research and applications. These facilities provide access to state-of-the-art technologies, equipment, and skilled personnel for a range of molecular biology techniques, primarily focused on DNA and RNA sequencing, genotyping, and related analyses. Their establishment and operation are critical for advancing scientific understanding, supporting public health initiatives, and fostering innovation in the agricultural and biomedical sectors within the country. The services offered are typically characterized by high-throughput capabilities, stringent quality control, and cost-effectiveness compared to individual laboratory setups.
| Who Needs Genomics Core Facilities? | Typical Use Cases |
|---|---|
| Academic Researchers: Scientists in universities and research institutes seeking to investigate genetic basis of diseases, understand biodiversity, or study evolutionary processes. | Public Health Professionals: Epidemiologists and public health officials investigating infectious disease outbreaks (e.g., pathogen surveillance, drug resistance profiling), genetic screening for inherited disorders, and population genetics studies for public health interventions. |
| Agricultural Scientists and Breeders: Researchers focused on crop improvement (e.g., identifying genes for yield, stress tolerance, nutritional value), livestock breeding for enhanced productivity and disease resistance, and conservation of genetic resources. | Biotechnology Companies and Startups: Emerging businesses requiring genomic data for product development, diagnostics, or R&D in areas such as drug discovery, agricultural biotechnology, or environmental monitoring. |
| Government Agencies and NGOs: Organizations involved in environmental conservation, biodiversity assessment, food security, and national health strategies. | Clinical Laboratories (Emerging): In the future, clinical settings may utilize these facilities for diagnostic purposes, personalized medicine initiatives, or pharmacogenomic studies. |
Key Services Offered by Genomics Core Facilities
- Next-Generation Sequencing (NGS) library preparation and sequencing (e.g., whole-genome sequencing, exome sequencing, transcriptome sequencing, targeted sequencing).
- Genotyping services (e.g., SNP arrays, microsatellite analysis).
- DNA/RNA extraction and quality assessment.
- Bioinformatics support for data analysis, interpretation, and storage.
- Method development and optimization for specific research projects.
- Training and capacity building for researchers in genomic techniques and data analysis.
Who Needs Genomics Core Facilities In Burkina Faso?
Genomics core facilities are essential for advancing scientific research, diagnostics, and innovation. In Burkina Faso, while still in its nascent stages, such facilities would serve a diverse range of stakeholders, empowering them with cutting-edge genomic technologies. These facilities would democratize access to advanced molecular tools, enabling local researchers and healthcare professionals to tackle national health challenges, improve agricultural yields, and contribute to biodiversity conservation.
| Target Customer/Department | Key Needs and Applications | Potential Impact |
|---|---|---|
| Academic Research Institutions (e.g., University Joseph Ki-Zerbo, CNRST) | Gene sequencing (DNA/RNA), gene expression analysis, genotyping, metagenomics for infectious diseases (malaria, neglected tropical diseases), non-communicable diseases, agricultural breeding, and ecological studies. | Enhanced understanding of local health burdens, development of novel diagnostic markers, improvement of crop varieties, and foundational research for innovation. |
| Public Health Laboratories (e.g., INSP, National Blood Transfusion Center) | Pathogen identification and surveillance, antimicrobial resistance profiling, outbreak investigations, genomic epidemiology, prenatal screening, and rare disease diagnostics. | Improved disease control strategies, rapid response to epidemics, enhanced blood safety, and early detection of genetic disorders. |
| Agricultural Research Centers (e.g., INERA) | Marker-assisted selection (MAS) for crop and livestock improvement, identification of genes for drought tolerance, disease resistance, and enhanced nutritional value, soil microbiome analysis. | Development of climate-resilient and higher-yielding crops and livestock, improved food security, and sustainable agricultural practices. |
| Environmental and Biodiversity Agencies (e.g., Ministry of Environment) | Species identification, population genetics for conservation, environmental DNA (eDNA) analysis for biodiversity monitoring, understanding ecosystem health, and tracking invasive species. | Effective conservation strategies, informed policy-making for biodiversity protection, and early warning systems for environmental threats. |
| Clinical Diagnostic Laboratories | Somatic mutation profiling for cancer, pharmacogenomics for personalized medicine, inherited disease testing, infectious disease diagnostics. | Improved patient outcomes through targeted therapies, reduced adverse drug reactions, and more accurate diagnosis of genetic conditions. |
| Biotechnology Startups and Companies | Genomic services for product development (e.g., diagnostics, biopesticides), contract research, and validation of biotechnological innovations. | Stimulation of the local biotech industry, creation of high-skilled jobs, and translation of research into marketable solutions. |
| Government Ministries (Health, Agriculture, Environment, Science & Technology) | Evidence-based policy formulation, national health surveillance programs, agricultural development plans, environmental management strategies, and investment in scientific infrastructure. | Informed decision-making, strategic allocation of resources, and national capacity building in genomics and related fields. |
| Non-Governmental Organizations (NGOs) | Genomic support for health programs (e.g., malaria elimination, HIV/AIDS research), agricultural development projects, and community-based conservation initiatives. | Enhanced effectiveness and impact of development programs through data-driven insights and advanced molecular tools. |
Target Customers and Departments
- Academic Research Institutions
- Public Health Laboratories
- Agricultural Research Centers
- Environmental and Biodiversity Agencies
- Clinical Diagnostic Laboratories
- Biotechnology Startups and Companies
- Government Ministries (Health, Agriculture, Environment, Science & Technology)
- Non-Governmental Organizations (NGOs) focused on health, agriculture, and conservation
Genomics Core Facilities Process In Burkina Faso
Genomics core facilities in Burkina Faso, like many in developing regions, are often characterized by resourcefulness and a focused approach to research needs. The workflow, from an initial inquiry to the execution of genomic services, typically involves several distinct stages, ensuring clarity, planning, and efficient use of often limited resources. This process is designed to accommodate a range of research projects, from small-scale academic studies to larger collaborative efforts, and emphasizes communication and technical proficiency. The following outlines the typical steps involved.
| Stage | Key Activities | Responsible Party | Outcome |
|---|---|---|---|
| Inquiry & Consultation | Researcher contacts facility; preliminary discussion of research needs. | Researcher, Genomics Facility Staff | Understanding of researcher's goals; initial project feasibility assessment. |
| Project Scoping & Proposal | Detailed discussion of objectives, sample types, desired outputs; proposal generation and quotation. | Genomics Facility Staff, Researcher | Agreed-upon project scope, detailed experimental plan, cost estimate. |
| Sample Submission & QC | Researcher submits samples; facility performs quality control checks. | Researcher, Genomics Facility Staff | High-quality, characterized samples ready for downstream processing. |
| Genomic Workflow Execution | DNA/RNA extraction, library preparation, sequencing, or other specific genomic assays. | Genomics Facility Staff | Generated raw genomic data or experimental results. |
| Data Analysis & Reporting | Bioinformatics processing, statistical analysis, report generation. | Genomics Facility Staff (Bioinformaticians), Researcher | Analyzed data, interpretation of results, comprehensive project report. |
| Data Delivery & Follow-up | Delivery of final data and report; post-delivery support. | Genomics Facility Staff, Researcher | Researcher has access to results for publication and further research; ongoing collaboration. |
Genomics Core Facilities Workflow in Burkina Faso
- Inquiry and Consultation: The process begins with a researcher or research team contacting the genomics core facility with a project idea or specific genomic need.
- Initial Assessment & Project Scoping: Facility staff engage in discussions with the inquirer to understand the project's objectives, sample types, desired outcomes, and any specific technical requirements. This stage helps determine the feasibility of the project within the facility's capabilities and resources.
- Proposal Development & Quotation: Based on the project scope, a detailed proposal is drafted. This includes outlining the proposed experimental workflow, required reagents and consumables, estimated timelines, and associated costs. A formal quotation is then provided to the researcher.
- Sample Submission & Quality Control: Upon agreement, researchers prepare and submit their biological samples according to the facility's guidelines. The facility performs rigorous quality control checks on incoming samples (e.g., DNA/RNA concentration, purity, integrity) to ensure their suitability for downstream genomic applications.
- Experimental Design & Optimization: For complex projects, the facility may assist in refining the experimental design and optimizing protocols to achieve the best possible results given the sample quality and research goals.
- Genomic Workflow Execution: This is the core of the service, involving specific molecular biology techniques such as DNA/RNA extraction, library preparation for sequencing (e.g., whole-genome, exome, transcriptome), PCR amplification, genotyping, or other targeted assays.
- Data Generation & Preliminary Analysis: Once experiments are complete, data is generated (e.g., sequencing reads from a sequencer). Basic quality checks on the raw data are performed.
- Data Processing & Analysis (if applicable): Depending on the service level, the facility may provide varying degrees of data analysis, from raw data output to bioinformatics processing, alignment, variant calling, and differential gene expression analysis. This often involves specialized bioinformatics expertise and software.
- Data Delivery & Reporting: The processed data, along with a comprehensive report detailing the methods used, results obtained, and any relevant interpretations, is delivered to the researcher in a standardized format.
- Follow-up & Support: The facility may offer post-delivery support to address any queries or assist with further interpretation of the results, fostering ongoing collaboration.
Genomics Core Facilities Cost In Burkina Faso
Genomics core facilities are crucial for advancing research and diagnostics in Burkina Faso. However, the cost of accessing these services can be a significant barrier. Several factors influence the pricing of genomic services, including the type of sequencing technology used, the complexity of the analysis, the volume of samples, and the expertise of the personnel involved. While precise pricing can fluctuate and is often negotiated based on project scope, general price ranges in the local currency (West African CFA franc - XOF) can be estimated. These estimates are based on typical costs for common genomic applications.
| Genomic Service (Example) | Typical Technology Used | Estimated Price Range (XOF) | Notes |
|---|---|---|---|
| Whole Genome Sequencing (Human/Large Mammal) | Illumina NovaSeq (High Throughput) | 150,000 - 500,000+ per sample | Includes library prep, sequencing, and basic bioinformatics. Excludes advanced analysis. |
| Exome Sequencing (Human) | Illumina MiSeq/NovaSeq | 80,000 - 300,000 per sample | Focuses on protein-coding regions. Price varies with enrichment method. |
| Targeted Sequencing (e.g., Gene Panel) | Illumina MiSeq | 50,000 - 200,000 per sample | Ideal for known gene mutations. Price depends on panel size. |
| RNA Sequencing (Transcriptomics) | Illumina NovaSeq/MiSeq | 100,000 - 400,000+ per sample | Requires quality RNA. Price varies with library type (e.g., stranded, poly-A selected) and depth. |
| Metagenomic Sequencing (e.g., Microbiome) | Illumina MiSeq | 70,000 - 250,000 per sample | Analysis complexity is a major cost driver. |
| DNA/RNA Extraction (Basic) | Manual or Automated Kits | 10,000 - 40,000 per sample | Price depends on sample type and extraction method. |
| Basic Bioinformatics Analysis (e.g., QC, Alignment) | In-house or Cloud | 20,000 - 100,000 per project/sample | Can be a significant portion of total cost for complex studies. |
Key Pricing Factors for Genomics Core Facilities in Burkina Faso:
- Sequencing Technology: Different platforms (e.g., Illumina NovaSeq, MiSeq, Oxford Nanopore) have varying per-base costs and upfront investment, impacting service pricing.
- Type of Genomics Application: Costs differ significantly between whole-genome sequencing (WGS), exome sequencing, targeted sequencing, RNA-Seq, epigenetics (e.g., methylation sequencing), and metagenomics.
- Sample Preparation: Complexity and cost of DNA/RNA extraction, library preparation, and quality control measures.
- Sequencing Depth and Read Length: Higher depth and longer reads generally lead to higher costs.
- Data Analysis and Bioinformatics Support: The level of bioinformatics expertise required for data processing, alignment, variant calling, annotation, and interpretation significantly impacts the final price.
- Consumables and Reagents: The cost of kits, enzymes, and other reagents specific to the chosen sequencing method.
- Personnel Costs: Salaries for skilled technicians, bioinformaticians, and researchers operating and maintaining the facility.
- Instrument Maintenance and Calibration: Ongoing costs associated with keeping sequencing machines operational and accurate.
- Throughput and Volume Discounts: Larger sample volumes often benefit from reduced per-sample pricing.
- Project Scope and Customization: Tailored experimental designs or specialized analyses will incur higher costs.
Affordable Genomics Core Facilities Options
Establishing and maintaining a genomics core facility can be a significant investment, but there are various strategies and options to make it more affordable. This guide explores affordable genomics core facility options, focusing on the value of 'value bundles' and practical cost-saving strategies. Value bundles often consolidate services and consumables, offering a more predictable and often reduced overall cost compared to procuring individual components. Cost-saving strategies encompass smart purchasing, shared resources, and optimized workflows.
| Value Bundle Type | Description | Potential Cost Savings | Considerations |
|---|---|---|---|
| Integrated Sequencing Kits | Bundles include library preparation reagents, sequencing adapters, and sometimes even a portion of the sequencing run cost. Eliminates the need to source individual components from multiple vendors. | 10-25% savings through bulk purchasing and bundled discounts. Reduced shipping costs and administrative overhead. | Requires compatibility with desired sequencing platforms. May limit flexibility in choosing specific reagents. |
| Comprehensive Workflow Packages | Offer a complete solution from sample input to data analysis for specific applications (e.g., whole-genome sequencing, RNA-Seq). Includes reagents, library prep, sequencing, and initial bioinformatics analysis. | 20-30% savings by integrating multiple steps. Predictable pricing for a complete project. Streamlined project management. | Less customizable than individual components. May include services or reagents not strictly required for every project. |
| Instrument & Consumable Leases/Service Agreements | Lease agreements often include maintenance and upgrades, bundled with the purchase of associated reagents or consumables. Predictable operational expenditure. | Reduced upfront capital expenditure. Bundled service can prevent costly downtime. Easier budgeting. | Long-term commitment required. May result in higher total cost over the instrument's lifespan compared to outright purchase. |
| 'Pay-as-you-go' with Discount Tiers | Offers a base rate for services with discounted pricing for higher volumes of usage within a defined period. Encourages consistent utilization. | Up to 15% savings for high-volume users. Incentivizes efficient use of facility resources. | Requires accurate forecasting of demand. May not be beneficial for users with sporadic or low-volume needs. |
| Collaborative Purchasing Groups | Multiple institutions or labs pooling their purchasing power to negotiate better bulk discounts on common reagents and consumables. | Significant savings (15-30%+) on high-volume items. Shared administrative burden. | Requires coordination and trust among participating entities. Potential for differing quality standards to be a concern. |
Key Cost-Saving Strategies for Genomics Core Facilities
- Strategic Procurement & Vendor Negotiations: Leverage bulk purchasing agreements, negotiate favorable pricing with suppliers for reagents and consumables, and consider multi-year contracts for predictable costs.
- Shared Instrumentation & Resource Pooling: Explore collaborations with other institutions or departments to share expensive equipment, reducing the capital expenditure for each entity.
- Optimized Workflow Design: Streamline experimental protocols to minimize reagent usage, reduce hands-on time, and increase throughput, thereby lowering per-sample costs.
- In-house vs. Outsourcing Analysis: Carefully evaluate whether certain data analysis services can be performed cost-effectively in-house versus outsourcing to specialized providers, considering personnel expertise and software costs.
- Grant Funding & Internal Subsidies: Actively pursue grant opportunities that support core facility development and operations. Secure internal institutional subsidies to offset operational expenses.
- Tiered Service Offerings: Implement different service levels (e.g., basic, standard, premium) with varying turnaround times and support, catering to diverse budget constraints.
- Consumable Management & Inventory Control: Implement robust inventory management systems to prevent waste, track usage, and identify opportunities for bulk discounts. Consider using compatible or third-party reagents where quality is assured.
- Staff Training & Cross-Training: Invest in comprehensive staff training to ensure efficient operation of instruments and diverse skill sets, reducing reliance on external technical support.
Verified Providers In Burkina Faso
In Burkina Faso, ensuring access to reliable healthcare is paramount. 'Verified Providers' refers to healthcare professionals and facilities that have undergone rigorous vetting processes to guarantee their legitimacy, qualifications, and adherence to ethical standards. This verification is crucial for patients seeking safe and effective medical care. Franance Health stands out as a leading organization in this space, offering a robust credentialing system that identifies and promotes the most competent and trustworthy healthcare providers in Burkina Faso. Their commitment to excellence means that when you choose a Franance Health credentialed provider, you are selecting a professional who has met stringent criteria, offering peace of mind and confidence in your healthcare decisions.
| Provider Type | Franance Health Verification Criteria | Why they are the best choice |
|---|---|---|
| Doctors (General & Specialists) | Medical degree from accredited institution, valid medical license, proof of ongoing professional development, clean disciplinary record. | Ensures they possess the latest knowledge and skills, are legally authorized to practice, and have a proven track record of ethical conduct. |
| Nurses & Midwives | Nursing or midwifery diploma/degree, valid professional license, completion of specialized training where applicable. | Guarantees they are trained to provide safe and competent care, particularly in maternal and child health, and adhere to professional nursing standards. |
| Pharmacies | Valid pharmacy license, proper storage and handling of medications, qualified pharmacists on duty, adherence to dispensing regulations. | Ensures access to authentic and safe medications, dispensed by qualified professionals, protecting patients from counterfeit or substandard drugs. |
| Hospitals & Clinics | Accreditation by relevant health authorities, presence of qualified medical staff, adherence to hygiene and safety protocols, availability of essential medical equipment. | Provides a safe and well-equipped environment for diagnosis and treatment, backed by competent healthcare professionals. |
Key Benefits of Choosing Franance Health Verified Providers
- Unwavering commitment to quality and patient safety.
- Highly qualified and licensed medical professionals.
- Adherence to international best practices and ethical guidelines.
- Access to modern medical facilities and equipment.
- Enhanced patient trust and confidence in healthcare services.
Scope Of Work For Genomics Core Facilities
This Scope of Work (SOW) outlines the technical deliverables and standard specifications expected from the Genomics Core Facilities. It aims to ensure consistent quality, efficient operation, and interoperability of services and data generated by the core.
| Service/Technology | Standard Specification | Deliverable Format | Quality Control Metrics |
|---|---|---|---|
| Whole Genome Sequencing (WGS) | Minimum 30x coverage for human genomes; appropriate coverage for other species based on project goals. | FASTQ, BAM/CRAM, VCF/BCF (for germline variants) | Per-base quality scores, insert size distribution, alignment rate, duplication rate, genome-wide variant statistics. |
| Whole Exome Sequencing (WES) | Minimum 100x average coverage on target regions; >80% of target regions covered at >20x. | FASTQ, BAM/CRAM, VCF/BCF (for germline variants) | On-target rate, mean coverage, coverage uniformity, duplication rate, variant annotation. |
| RNA Sequencing (RNA-Seq) | Sufficient depth to capture expressed transcripts; minimum 30 million reads per sample for bulk RNA-Seq. | FASTQ, BAM/CRAM, Gene counts/TPM/FPKM matrices | Read quality, alignment rate, uniquely mapped reads, gene body coverage, outlier gene expression detection. |
| Single Cell RNA Sequencing (scRNA-Seq) | Sufficient cell capture and sequencing depth per cell to resolve cell-type specific expression. | FASTQ, BAM/CRAM, Cell barcode/UMI counts, Gene expression matrices (per cell) | Cells detected, genes detected per cell, total UMI counts per cell, mitochondrial gene percentage, cell clustering quality. |
| ChIP Sequencing (ChIP-Seq) | Sufficient sequencing depth to identify peaks; minimum 20 million reads per sample. | FASTQ, BAM/CRAM, Peak files (BED format) | Signal-to-noise ratio, peak number and distribution, motif analysis, MACS score. |
| Library Preparation (General) | Utilization of validated protocols and reagents; strict adherence to contamination control measures. | N/A | Library yield, fragment size distribution, adapter dimer percentage. |
| Data Storage and Access | Secure and reliable storage of raw and processed data for a minimum of [Specify Duration, e.g., 5 years]. | Access via secure network protocols (e.g., SFTP, HTTPS) or dedicated storage solutions. | Data integrity checks, backup frequency. |
Technical Deliverables
- Raw sequencing data (FASTQ format) for all generated libraries.
- Aligned sequencing data (BAM/CRAM format) with associated index files.
- Variant call files (VCF/BCF format) for germline and somatic variant analysis, where applicable.
- Gene expression quantification data (e.g., TPM, FPKM, count matrices) in TSV or CSV format.
- Metadata associated with each sample and experiment, including experimental design, sample origin, processing details, and quality control metrics.
- Quality control reports for raw reads, alignment, and variant calling/expression quantification.
- Custom analysis reports, if specified in individual project requests.
- Access to or provision of processed data in a standardized, queryable format (e.g., databases, APIs).
- Standard Operating Procedures (SOPs) for all core services.
Service Level Agreement For Genomics Core Facilities
This Service Level Agreement (SLA) outlines the guaranteed response times and uptime for the Genomics Core Facilities. It aims to ensure reliable and timely access to critical genomic services for researchers.
| Service Category | Response Time Guarantee (Business Hours) | Uptime Guarantee (%) | Notes |
|---|---|---|---|
| Sequencing Services (Initial Consultation & Planning) | 2 Business Days | 99.5% | Applies to initial communication and project scoping meetings. |
| Sequencing Services (Sample Receipt & QC Notification) | 1 Business Day | 99.5% | Notification upon successful receipt and initial quality check of samples. |
| Sequencing Services (Data Delivery - Raw Data) | Varies by platform (e.g., Illumina: 7-14 days, PacBio/ONT: 14-30 days, post-library prep completion) | 98.0% | Estimated turnaround times provided at project initiation. 'Post-library prep completion' is the start of this count. |
| Genotyping Services (Sample Receipt & QC Notification) | 1 Business Day | 99.5% | Notification upon successful receipt and initial quality check of samples. |
| Genotyping Services (Data Delivery - Raw Data) | 5-10 Business Days (post-library prep completion) | 98.0% | Estimated turnaround times provided at project initiation. |
| RNA-Seq and Gene Expression Analysis (Sample Receipt & QC Notification) | 1 Business Day | 99.5% | Notification upon successful receipt and initial quality check of samples. |
| RNA-Seq and Gene Expression Analysis (Data Delivery - Raw Data) | 7-14 Business Days (post-library prep completion) | 98.0% | Estimated turnaround times provided at project initiation. |
| Bioinformatics Support (Initial Inquiry Response) | 2 Business Days | N/A | For questions regarding data analysis, software, or troubleshooting. |
| Bioinformatics Support (Analysis Ticket - Basic) | 3-5 Business Days (for simple requests, e.g., QC reports) | N/A | Response and estimated completion time for standard analysis tasks. |
| Bioinformatics Support (Analysis Ticket - Complex) | 5-10 Business Days (for complex requests, e.g., de novo assembly, variant calling pipelines) | N/A | Response and estimated completion time for advanced analysis tasks. Subject to project scope. |
| Sample Processing and QC (Standard Assays - e.g., DNA/RNA quantification, smear microscopy) | 2-3 Business Days | 99.0% | For routine sample processing and quality control steps. |
| Sample Processing and QC (Complex Assays - e.g., Bioanalyzer, TapeStation) | 3-5 Business Days | 99.0% | For more involved sample quality assessment. |
Key Service Categories
- Sequencing Services (e.g., Illumina, PacBio, Oxford Nanopore)
- Genotyping Services (e.g., SNP arrays, ddRAD-seq)
- RNA-Seq and Gene Expression Analysis
- Bioinformatics Support
- Sample Processing and QC
Frequently Asked Questions

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